Home - Products - PROTACs - PROTAC - Hexane-1,6-diyldiphosphonic acid

Hexane-1,6-diyldiphosphonic acid

CAS No. 4721-22-6

Hexane-1,6-diyldiphosphonic acid( —— )

Catalog No. M33381 CAS No. 4721-22-6

Hexane-1,6-diyldiphosphonic acid (1,6-Hexanebisphosphonic acid) is a PROTAC linker based on the alkyl chain.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 33 In Stock
10MG 49 In Stock
25MG 82 In Stock
50MG 122 In Stock
100MG 212 In Stock
200MG 268 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Hexane-1,6-diyldiphosphonic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Hexane-1,6-diyldiphosphonic acid (1,6-Hexanebisphosphonic acid) is a PROTAC linker based on the alkyl chain.
  • Description
    Hexane-1,6-diyldiphosphonic acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
  • In Vitro
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    PROTACs
  • Target
    PROTAC
  • Recptor
    PROTAC Linker
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    4721-22-6
  • Formula Weight
    246.14
  • Molecular Formula
    C6H16O6P2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(P(=O)(O)O)CCCCCP(=O)(O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562?
molnova catalog
related products
  • MZ1

    MZ1 is a?PROTAC that tethers JQ1 to a ligand for the E3 ubiquitin ligase VHL, triggers, induces degradation of the BET bromodomain BRD4.

  • SNIPER(AR)-51

    SNIPER(AR)-51 is a specific and nongenetic, protein degradation inducer of androgen receptor, consistiong of AR ligand and IAP ligand and linker; induces proteasomal degradation of AR and shows effective protein knockdown activity.

  • Azido-PEG10-alcohol

    Azido-PEG10-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs